Serotonin receptors are important components of the serotonin system, which plays a crucial role in various physiological functions and behaviors, including mood regulation, sleep, appetite, and pain perception. Serotonin receptors are proteins located on the surface of cells that bind with serotonin molecules, triggering a variety of cellular responses. There are several subtypes of serotonin receptors, classified into seven families (5-HT1 to 5-HT7) based on their molecular structure and function. These receptors are widely distributed throughout the central nervous system and peripheral tissues, and they mediate the effects of serotonin neurotransmission. Research on serotonin receptors aims to understand their role in various physiological and pathological processes, as well as to develop novel pharmacological agents targeting these receptors for the treatment of psychiatric disorders, such as depression, anxiety, and schizophrenia, as well as other conditions like migraine, irritable bowel syndrome, and fibromyalgia. Advances in this field have provided valuable insights into the complex mechanisms underlying serotonin signaling and have led to the identification of potential therapeutic targets for a range of neurological and psychiatric disorders.